a drug that acts on the central nervous system to suppress the appetite: it inhibits the reuptake of noradrenaline and serotonin. Sibutramine is used in the treatment of obesity; it is prescribed mainly for those with a body mass index of 30 or over who have failed to respond to standard weight-reduction measures. It is administered by mouth; side-effects include dry mouth, constipation, and insomnia.
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  • Sibutramine — Systematic (IUPAC) name (±) dimethyl 1 [1 (4 chlorophenyl) cyclobutyl] …   Wikipedia

  • Sibutramine — Énantiomère S de la sibutramine (en haut) et R sibutramine (en bas) Général …   Wikipédia en Français

  • sibutramine — si·bu·tra·mine sə byü trə .mēn, mən n an appetite suppressant that is administered orally in the form of its hydrated hydrochloride C17H26ClN·HCl·H2O in the treatment of obesity and that exerts its therapeutic effect by inhibiting the reuptake of …   Medical dictionary

  • sibutramine — si·bu·tra·mine (sə byo͞oʹtrə mĭn, mēn ) n. A drug that suppresses appetite by inhibiting the reuptake of the neurotransmitters norepinephrine and serotonin, used in the management of obesity.   [Alteration of cyclo + butyl + perhaps tri (from its …   Universalium

  • sibutramine — noun A synthetic drug used to suppress appetite in the treatment of obesity …   Wiktionary

  • sibutramine hydrochloride — si·bu·tra·mine hy·dro·chlo·ride (sĭ buґtrə mēn) an inhibitor of norepinephrine and serotonin reuptake, structurally related to amphetamine, used as an anorectic in the management of obesity; withdrawn from the market …   Medical dictionary

  • 106650-56-0 — Sibutramine Sibutramine Général No CAS …   Wikipédia en Français

  • C17H26ClN — Sibutramine Sibutramine Général No CAS …   Wikipédia en Français

  • Anti-obesity medication — Orlistat (Xenic …   Wikipedia

  • Management of obesity — The main treatment for obesity consists of dieting and physical exercise.[1] Diet programs may produce weight loss over the short term,[2] but maintaining this weight loss is frequently difficult and often requires making exercise and a lower… …   Wikipedia

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